Deine Übereinstimmung

Skills

biopharmaceuticsADMERegulatory submissionsClinical trialsAttention to detailData AnalysisPharmacokineticsDMPK in-vitroDrug Delivery SystemsFormulation designProject management softwareDrug-Drug Interaction Assessment

Sprachen

Englisch

Vergütung

Expected Annual Base Salary Range for role: 122,500.00 - 227,500.00 CHF

Die Stelle

01Expert PBPK modeler to provide translational modeling support for global drug discovery and development projects

02Perform translational PBPK analyses to predict clinical drug exposure in specific populations, assess potential for DDI, understand clinical impact of disease on drug exposure, as well as apply biopharmaceutic PBPK modeling to support formulation changes and achieve clinical biowaivers

03Integrate PK/ PD data, ADME and DDI findings

04Ability to interpret and communicate modeling results and potential impact to project teams

05Prepare summary documents for use in regulatory submissions and ability to respond independently to health authority questions

Anforderungen

↳PhD in pharmaceutical sciences or related discipline with experience in ADME/DMPK sciences, biopharmaceutics, and modeling and simulation.

↳At least 5+ years in pharmaceutical industry including demonstrated knowledge and experience with PBPK modeling.

↳Hands on experience with PBPK modeling tools such as PK-Sim, Simcyp, or GastroPlus is required.

↳In addition, experience with modeling software such as Monolix, R, Phoenix, or Nonmem is desired.

↳Experience in authoring regulatory documents, knowledge of global regulatory requirements and guidance

↳Broad knowledge of drug discovery and development, e.g., pharmacokinetics, drug delivery, formulation, ADME, DDI, etc.

Vorteile

＋In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters.

＋We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs.

＋In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave.

＋Long-term equity awards granted at group level may also be part of your package.

Technologien

GastroPlusSimcypPK-SimMonolixRPhoenixNonmem

Unternehmen

Novartis

Pharmaceuticals

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