Senior NGS Bioinformatician

Position

Vollzeit

Festanstellung

Senior

Wissenschaft & Forschung

Konditionen

Rolle, Switzerland

Hybrid

60–100%

USD 71,250-143,750 (Massachusetts); varies in other locations.

Anforderungen

5+ J. Erfahrung

Doktortitel

Sprachen

Englisch C1

Vergütung

USD 71,250-143,750 (Massachusetts); varies in other locations.

Beschreibung

As our Senior NGS Bioinformatician, your role will span the full lifecycle of bioinformatics product development - from exploratory research and feasibility studies to analytical validation and IVD/CDx development under regulated frameworks.

Aufgaben

Design and execute analytical and exploratory studies across diverse NGS datasets
Evaluate and improve algorithmic performance across variant classes and technologies
Explore emerging sequencing technologies and bioinformatics methods
Conduct deep-dive analyses to generate biological insights from complex datasets
Design and statistically analyze analytical validation studies (sensitivity, specificity, precision, accuracy, LoD, LoB)
Contribute to performance evaluation documentation supporting IVD/CDx development
Contribute code to production-grade NGS pipelines, ensuring robustness, reproducibility, and performance
Contribute to scientific publications, white papers, or conference presentations
Contribute to projects with external collaborators, including project planning, data analysis and results presentation

Anforderungen

PhD in Bioinformatics / Computational Biology (or equivalent industry experience)
5+ years of experience in NGS data analysis in academic, biotech, or diagnostics environments
Experience analyzing somatic variants (SNVs, indels, CNVs, fusions) in oncology NGS assays
Experience with targeted panel sequencing and/or hybrid capture technologies
Strong proficiency in Python and/or R for statistical analysis and data exploration
Experience working with workflow management systems (e.g., Nextflow or similar) is highly desirable
Excellent communication & presentation skills (English is a must, any other language is an asset)

Technologien

PythonRNextflow

Vorteile

Sickness and Accident coverage through Helsana
Meal Vouchers at 90CHF PM with our partner cafeteria
A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit
Free parking in an easy to access location
A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding
Direct interaction and exposure to senior leadership and our executive team locally

Unternehmen

SOPHiA GENETICS

Biotechnology

SOPHiA GENETICS is a global leader in data-driven medicine, providing innovative solutions for healthcare professionals to improve patient outcomes.