The PostDoc research will be part of a multi-center research project on applying and combining multi-modal 2D and 3D imaging methods for understanding metastasis and tumor deposit formation in colorectal tumors. Specifically, the work will focus on optimizing 3D X-ray virtual histology methods by phase-contrast micro-CT and corresponding image processing techniques also with view on combining it with other 2D and 3D techniques such as H&E and LSFM. The work will be done in close cooperation and synergy with an already running PhD project. Partly existing database will be used and extended to develop image processing pipelines and models for the automated evaluation of 3D data sets towards answering clinical research questions. The project is highly interdisciplinary and is carried out in close collaboration with imaging, image analysis and clinical experts from Switzerland and abroad. Involvement in other closely related research activities of the imaging group at the X-ray Center is also foreseen.