Student Internship on Gene Therapy Bioassay and Formulation Development in Pharmaceutical Development (Basel, 6-12 months)

Role

Full-time

Intern

Other

Logistics

Basel

Closes in 30 days

Requirements

Bachelor's

EU/EFTA permit

Skills

Cell cultureGene therapyrAAV handlingRNA isolationGoogle SheetsGraphPad PrismJMPData AnalysisqPCRExcelDocumentationLiquid chromatography

Description

The Opportunity In Roche’s PTD Biologics Pharmaceutical Development (PTDP), we are responsible for the technical development and preparation of sterile dosage forms of biotechnologically and chemically engineered molecules, including gene therapies. We are now offering a unique opportunity to join our team in Basel and contribute to the formulation development of novel gene therapies by supporting protocol and sample preparation for laboratory activities, performing advanced analytics to assess the quality attributes of the prepared formulations, and a particular focus on setting up and executing a cell-based functional assay. If you are curious, willing to learn and work in a highly collaborative and supportive international team environment, we are looking forward to receiving your application.

Responsibilities

Working safely and responsibly in a BSL-2 laboratory environment, handling mammalian cells and recombinant adeno-associated viral vectors (rAAVs)
Carrying out day-to-day cell culture activities
Establishing a cell-based assay to assess the stability of rAAV formulations
Learning and performing relevant analytics such as dd/qPCR, flow cytometry, HPLC, DLS, etc and the associated preparatory procedures, such as RNA isolation
Planning your studies in line with the concurrent needs and timelines and preparing your protocols
Performing experiments, recording, analysing, and presenting your data to the local and broader teams
Opportunity to engage in departmental activities related to innovative formulations, processes, and technologies

Requirements

You must either be currently enrolled at a university in pharmaceutical sciences, chemistry, biotechnology, chemical engineering, mechanical engineering, biology or a related field pursuing a Bachelor's or Master's degree; or have completed your studies (passed the 2nd state examination of your pharmacy studies) within the past 12 months prior to the starting date with a Bachelor's or Master's degree.
Cell culture experience and experience of working in the lab without direct supervision (e.g. on a research project) is necessary
Previous experience with molecular and/or biophysical analytical methods used in gene therapy formulation development is desirable
Demonstrate efficient time management, planning, and appropriate record-keeping, with previous experience using electronic lab books being desirable.
Understand data analysis and visualization.
Previous experience analyzing data using MS Excel, Google Sheets, GraphPad Prism, R, JMP, or other analysis software would be an advantage.
Bring curiosity, adaptability, willingness to learn and support the team, collaborative spirit, openness to different working styles.
Work independently on small projects in the laboratory and/or support challenging aspects of ongoing projects.
Build technical documentation, present results in internal meetings, learn how current industrial requirements are implemented in everyday life, and gain insights into the multifaceted and diverse working environment of pharmaceutical development.

Benefits

Additional Information Preferred start date: September 2026; please clearly indicate your availability for the internship (min. 6 months) in your cover letter. Applications need to include a CV and a motivation letter. For Non-EU/EFTA citizens: due to regulations, you must provide a mandatory letter issued by your university stating that an Internship is mandatory for your studies (for both 6 months and longer). For an internship lasting longer than 6 months, it also needs to specify the required length of the internship. Please upload this mandatory letter and your enrollment certificate along with your CV and motivation letter. Ready to take the next step? We'd love to hear from you. Apply now to explore this exciting opportunity!

Company

Roche

Pharmaceuticals

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.