Your position This project addresses that limitation by designing ultrasmall nanoparticles suitable for intravenous delivery and tumor targeting, with a specific focus on neuroblastoma. Building on established expertise in nanoparticle synthesis and surface chemistry, this project will optimize nanomaterial design for circulation, targeting, and therapeutic performance in neuroblastoma organoids, enabling preclinical evaluation in physiologically relevant 3D models. This PhD position sits at the interface of nanochemistry, and translational cancer research, and offers the opportunity to contribute to a next-generation strategy for making radiotherapy more selective, effective, and clinically accessible for difficult-to-treat pediatric tumors.